{"id":3874,"date":"2018-01-29T10:59:53","date_gmt":"2018-01-29T10:59:53","guid":{"rendered":"https:\/\/www.nanexa.com\/mfn_news\/nya-djurstudieresultat-visar-pa-mojligheter-for-langa-depaer-med-pharmashell\/"},"modified":"2018-01-29T10:59:53","modified_gmt":"2018-01-29T10:59:53","slug":"nya-djurstudieresultat-visar-pa-mojligheter-for-langa-depaer-med-pharmashell","status":"publish","type":"mfn_news","link":"https:\/\/nanexa.com\/sv\/mfn_news\/nya-djurstudieresultat-visar-pa-mojligheter-for-langa-depaer-med-pharmashell\/","title":{"rendered":"Nya djurstudieresultat visar p\u00e5 m\u00f6jligheter f\u00f6r l\u00e5nga dep\u00e5er med PharmaShell\u00ae"},"content":{"rendered":"
<\/strong><\/div>\n

Pressmeddelande<\/p>\n

Uppsala 2018-01-29<\/p>\n

Nya djurstudieresultat visar p\u00e5 m\u00f6jligheter f\u00f6r l\u00e5nga dep\u00e5er med PharmaShell\u00ae<\/p>\n

Nanexa har nu erh\u00e5llit resultat fr\u00e5n en PK-studie* i r\u00e5tta d\u00e4r flera doser av en l\u00e4kemedelssubstans belagd med PharmaShell\u00ae av olika skaltjocklekar har unders\u00f6kts.<\/p>\n

Fr\u00e5n en f\u00f6reg\u00e5ende djurstudie drogs slutsatsen att dep\u00e5funktionen hos PharmaShell\u00ae varade l\u00e4ngre \u00e4r de tre veckor som den studien p\u00e5gick. Syftet med djurstudien vi nu f\u00e5tt resultat fr\u00e5n var att se hur l\u00e4nge vi kunde uppr\u00e4tth\u00e5lla en dep\u00e5 med stabil l\u00e4kemedelsfris\u00e4ttning i f\u00f6rs\u00f6ksdjuren genom att ta blodprover under tre m\u00e5nader.<\/p>\n

Resultaten visar att vi lyckades styra dep\u00e5l\u00e4ngderna mellan 6 veckor och minst tre m\u00e5nader, som var studiens l\u00e4ngd. Ber\u00e4kningar utifr\u00e5n studieresultaten indikerar \u00e4ven att de l\u00e4ngsta dep\u00e5erna i studien kan bibeh\u00e5llas i upp till ett \u00e5r.<\/p>\n

Nanexas VD David Westberg kommenterar:<\/p>\n

"Med de djurstudier vi utf\u00f6rt under 2017 och i b\u00f6rjan av 2018 har vi nu visat att vi har full frihet att designa l\u00e4kemedelsdep\u00e5er med PharmaShell\u00ae. Vi har m\u00f6jlighet att styra 'bursteffekten' (den initiala halten av l\u00e4kemedel som fris\u00e4tts), l\u00e4ngden p\u00e5 dep\u00e5erna, fr\u00e5n korta dep\u00e5er till riktigt l\u00e5nga, samt halten l\u00e4kemedel i blodet under dep\u00e5tiden. Genom dessa resultat ser vi att PharmaShell\u00ae \u00e4r en v\u00e4ldigt flexibel drug delivery- plattform som \u00f6ppnar f\u00f6r en m\u00e4ngd olika till\u00e4mpningar, vilket s\u00e5 klart \u00e4r en stor f\u00f6rdel i v\u00e5ra samtal med l\u00e4kemedelsf\u00f6retag.<\/p>\n

Djurstudieresultaten \u00e4r ocks\u00e5 viktiga och h\u00f6gst anv\u00e4ndbara f\u00f6r v\u00e5rt egna projekt f\u00f6r att v\u00e4gleda oss i valet av onkologisk indikation samt l\u00e4kemedel."<\/p>\n

Denna information \u00e4r s\u00e5dan information som Nanexa AB \u00e4r skyldigt att offentligg\u00f6ra enligt EU:s marknadsmissbruksf\u00f6rordning. Informationen l\u00e4mnades, genom ovanst\u00e5ende kontaktpersons f\u00f6rsorg, f\u00f6r offentligg\u00f6rande den 29 januari, 2018.<\/p>\n

F\u00f6r mer information kontakta:
David Westberg – VD, Nanexa AB (publ) Telefon: 0709 – 42 83 03
E-post: david.westberg@nanexa.se www.nanexa.com<\/p>\n

Om Nanexa AB (publ)<\/p>\n

Nanexa AB \u00e4r ett nanoteknologiskt drug delivery-f\u00f6retag som fokuserar verksamheten p\u00e5 utvecklingen av PharmaShell\u00ae som \u00e4r ett nytt och banbrytande drug delivery-system som bed\u00f6ms ha en stor potential inom ett flertal indikationsomr\u00e5den. Inom ramen f\u00f6r PharmaShell\u00ae har Nanexa samarbetsavtal med bland andra AstraZeneca.<\/p>\n

*En farmakokinetisk studie (PK-studie) \u00e4r en studie av hur en l\u00e4kemedelssubstans p\u00e5verkas vid administrering till en levande organism. I en farmakokinetisk studie f\u00f6ljs vanligtvis l\u00e4kemedelssubstansen genom att ta blodprover fr\u00e5n organismen vid ett flertal tidpunkter f\u00f6r att kunna m\u00e4ta halten av den.\u00a0<\/p>\n

\n

Bifogade filer<\/strong><\/p>\n\n

<\/a><\/p>\n<\/div>\n

<\/div>\n","protected":false},"excerpt":{"rendered":"

Pressmeddelande<\/p>\n

Uppsala 2018-01-29<\/p>\n

Nya djurstudieresultat visar p\u00e5 m\u00f6jligheter f\u00f6r l\u00e5nga dep\u00e5er med PharmaShell\u00ae<\/p>\n

Nanexa har nu erh\u00e5llit resultat fr\u00e5n en PK-studie* i r\u00e5tta d\u00e4r flera doser av en l\u00e4kemedelssubstans belagd med PharmaShell\u00ae av olika skaltjocklekar har unders\u00f6kts.<\/p>\n

L\u00e4s mer<\/a><\/p>\n","protected":false},"template":"","class_list":["post-3874","mfn_news","type-mfn_news","status-publish","hentry","mfn-news-tag-mfn-ci_sv","mfn-news-tag-mfn-type-ir_sv","mfn-news-tag-mfn-regulatory-mar_sv","mfn-news-tag-mfn_sv","mfn-news-tag-mfn-ci-other_sv","mfn-news-tag-mfn-regulatory_sv","mfn-news-tag-mfn-lang-sv_sv"],"acf":[],"yoast_head":"\nNya djurstudieresultat visar p\u00e5 m\u00f6jligheter f\u00f6r l\u00e5nga dep\u00e5er med PharmaShell\u00ae - Nanexa AB<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/nanexa.com\/mfn_news\/nya-djurstudieresultat-visar-pa-mojligheter-for-langa-depaer-med-pharmashell\/\" \/>\n<meta property=\"og:locale\" content=\"sv_SE\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Nya djurstudieresultat visar p\u00e5 m\u00f6jligheter f\u00f6r l\u00e5nga dep\u00e5er med PharmaShell\u00ae - 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