{"id":3895,"date":"2017-09-12T07:36:34","date_gmt":"2017-09-12T07:36:34","guid":{"rendered":"https:\/\/www.nanexa.com\/mfn_news\/positiva-sakerhetsresultat-fran-djurstudie-med-pharmashell\/"},"modified":"2017-09-12T07:36:34","modified_gmt":"2017-09-12T07:36:34","slug":"positiva-sakerhetsresultat-fran-djurstudie-med-pharmashell","status":"publish","type":"mfn_news","link":"https:\/\/nanexa.com\/sv\/mfn_news\/positiva-sakerhetsresultat-fran-djurstudie-med-pharmashell\/","title":{"rendered":"Positiva s\u00e4kerhetsresultat fr\u00e5n djurstudie med PharmaShell\u00ae"},"content":{"rendered":"
Efter djurstudien som Nanexa genomf\u00f6rde under innevarande kvartal<\/p>\n

analyserades v\u00e4vnad hos f\u00f6rs\u00f6ksdjuren med avseende p\u00e5 metallinneh\u00e5ll.<\/p>\n

Resultaten fr\u00e5n studien visar att ingen ansamling av metall f\u00f6rekommer i lever,<\/p>\n

mj\u00e4lte, lungor eller hj\u00e4rna.<\/strong><\/div>\n

PharmaShell\u00ae utg\u00f6rs av skal av metalloxid (i det studerade fallet aluminiumoxid) som<\/p>\n

appliceras direkt p\u00e5 partiklar av l\u00e4kemedel och ger en helt t\u00e4t inneslutning av<\/p>\n

partiklarna. Detta kan ge m\u00f6jlighet till styrning av l\u00e4kemedelsfris\u00e4ttningen samt ett<\/p>\n

flertal andra f\u00f6rdelar.<\/p>\n

I kontakter med l\u00e4kemedelsindustrin har fr\u00e5gan rests om metall fr\u00e5n PharmaShell\u00ae<\/p>\n

anrikas i organ s\u00e5som lever, mj\u00e4lte, lungor eller hj\u00e4rna. F\u00f6r att verifiera att s\u00e5 inte \u00e4r<\/p>\n

fallet har v\u00e4vnadsprover fr\u00e5n kritiska organ tagits efter avslutad djurstudie och sedan<\/p>\n

analyserats med avseende p\u00e5 aluminium.<\/p>\n

Aluminiumniv\u00e5erna i organen hos r\u00e5ttor som f\u00e5tt PharmaShell\u00ae injicerat \u00f6verstig inte<\/p>\n

aluminiuminneh\u00e5llet i organen hos kontrollgruppen, d v s ingen anrikning av<\/p>\n

aluminium i organv\u00e4vnaden kunde p\u00e5visas.<\/p>\n

F\u00f6retagets VD David Westberg kommenterar<\/p>\n

Under produktutveckling av l\u00e4kemdel som bygger p\u00e5 nya drug delivery-system<\/p>\n

uppkommer ofta fr\u00e5gan om biodistribution, dvs om material fr\u00e5n drug delivery<\/p>\n

plattformen i sig, anrikas i vitala organ s\u00e5som lever, mj\u00e4lte, lungor och hj\u00e4rna. D\u00e4rf\u00f6r<\/p>\n

var det naturligt f\u00f6r oss att unders\u00f6ka detta i den djurstudie i r\u00e5tta som vi just<\/p>\n

genomf\u00f6rt f\u00f6r att studera dep\u00e5effekten av PharmaShell\u00ae.<\/p>\n

Dessa resultat st\u00e4rker Nanexas position i samtal med framtida partners fr\u00e5n<\/p>\n

l\u00e4kemedelsindustrin.<\/p>\n

F\u00f6r mer information kontakta:<\/p>\n

David Westberg – VD, Nanexa AB (publ)<\/p>\n

Telefon: 0709 -42 83 03<\/p>\n

E-post: david.westberg@nanexa.se<\/p>\n

www.nanexa.se<\/p>\n

Denna information \u00e4r s\u00e5dan information som Nanexa AB \u00e4r skyldigt att offentligg\u00f6ra enligt EU:s<\/p>\n

marknadsmissbruksf\u00f6rordning. Informationen l\u00e4mnades, genom ovanst\u00e5ende kontaktpersons f\u00f6rsorg,<\/p>\n

f\u00f6r offentligg\u00f6rande den 12 september, 2017.<\/p>\n

Om Nanexa AB (publ)<\/p>\n

Nanexa AB \u00e4r ett nanoteknologiskt drug deliveryf\u00f6retag som fokuserar verksamheten p\u00e5 utvecklingen<\/p>\n

av PharmaShell\u00ae som \u00e4r ett nytt och banbrytande drug delivery-system som bed\u00f6ms ha en stor<\/p>\n

potential inom ett flertal indikationsomr\u00e5den. Inom ramen f\u00f6r PharmaShell\u00ae har Nanexa<\/p>\n

samarbetsavtal med bland andra AstraZeneca och Karolinska Institutet.<\/p>\n

\n

Bifogade filer<\/strong><\/p>\n\n

<\/a><\/p>\n<\/div>\n

<\/div>\n","protected":false},"excerpt":{"rendered":"

Efter djurstudien som Nanexa genomf\u00f6rde under innevarande kvartal analyserades v\u00e4vnad hos f\u00f6rs\u00f6ksdjuren med avseende p\u00e5 metallinneh\u00e5ll. Resultaten fr\u00e5n studien visar att ingen ansamling av metall f\u00f6rekommer i lever, mj\u00e4lte, lungor eller hj\u00e4rna.<\/p>\n","protected":false},"template":"","class_list":["post-3895","mfn_news","type-mfn_news","status-publish","hentry","mfn-news-tag-mfn-ci_sv","mfn-news-tag-mfn-type-ir_sv","mfn-news-tag-mfn-regulatory-mar_sv","mfn-news-tag-mfn_sv","mfn-news-tag-mfn-ci-other_sv","mfn-news-tag-mfn-regulatory_sv","mfn-news-tag-mfn-lang-sv_sv"],"acf":[],"yoast_head":"\nPositiva s\u00e4kerhetsresultat fr\u00e5n djurstudie med PharmaShell\u00ae - Nanexa AB<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/nanexa.com\/mfn_news\/positiva-sakerhetsresultat-fran-djurstudie-med-pharmashell\/\" \/>\n<meta property=\"og:locale\" content=\"sv_SE\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Positiva s\u00e4kerhetsresultat fr\u00e5n djurstudie med PharmaShell\u00ae - Nanexa AB\" \/>\n<meta property=\"og:description\" content=\"Efter djurstudien som Nanexa genomf\u00f6rde under innevarande kvartal analyserades v\u00e4vnad hos f\u00f6rs\u00f6ksdjuren med avseende p\u00e5 metallinneh\u00e5ll. 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